
Now's the Time! Don't let vaginal discomfort hold you back. Osphena® - a key to unlocking better vaginal health and comfort

Osphena® is the first and only once-daily, oral, non-hormonal prescription treatment for moderate to severe vaginal dryness and/or moderate to severe painful intercourse, symptoms of changes in and around your vagina due to menopause (known as vulvar and vaginal atrophy or VVA).
Hot flashes and other early menopause symptoms may fade, but vaginal dryness and painful sex due to menopause often show up later—and they can become more bothersome over time. The good news is, you don't have to just live with them.
Over time, many women find that vaginal discomfort becomes one of their most frustrating menopause symptoms. That's why having an oral treatment, like Osphena®, that directly targets this discomfort can make such a difference.
The most common side effects include hot flashes, vaginal discharge, muscle spasms, headache, excessive sweating, heavy vaginal bleeding, and night sweats.
Menopause may change your body — but you call the shots.
Why Osphena?
Osphena® is a non-hormonal, oral prescription pill that could be the key you need to relieve symptoms of moderate to severe vaginal dryness and/or pain during sex due to menopause.
Osphena® has targeted on-site action in the vaginal tissue to lower vaginal pH, and improve overall vaginal health.
Many women choose Osphena® because it's a once daily option that directly treats the vaginal tissue - not just a temporary relief from symptoms. Simply take one Osphena® tablet daily with a meal.
Osphena® offers meaningful relief without any vaginal application. For many women, that's a big advantage—vaginal products can feel awkward, messy, or disruptive. An oral medication may be simpler, more private, and easier to fit into everyday life.
Think of Osphena® as a smart key: it's not an estrogen, but it selectively activates or “unlocks” estrogen receptors in the vaginal area where treatment is needed. This can be appealing for women who:
- Are experiencing specific vaginal symptoms after menopause as their most bothersome symptoms
- Are over the age where starting menopause hormone therapy as a treatment for vaginal dryness/painful sex is generally not recommended
- Cannot use or prefer not to use estrogen-based treatments due to medical history or other factors
For many women, Osphena® offers effective relief for these VVA symptoms without the use of estrogens – and it's an oral pill, so nothing has to be applied vaginally.
Osphena® has a BOXED WARNING for Endometrial Cancer and Cardiovascular Disorders.
Why Osphena?Need a Healthcare Provider who Understands Menopause?
You are not alone – and you deserve a supportive, judgement-free conversation on treatment options for your menopausal symptoms.
Actor Portrayal
Are you struggling with vaginal dryness and/or painful sex after menopause? Osphena® is a key step towards better vaginal health
Watch video to learn moreAfter menopause, your body makes much less estrogen - the hormone that helps keep vaginal tissue healthy. With less estrogen, the tissue can become thinner, dryer, and more delicate - a condition called vulvovaginal atrophy (VVA). The two symptoms women usually find most bothersome are vaginal dryness and painful sex.
Reducing dryness is essential for healthy skin, and your vaginal tissue is no different.
When vaginal dryness and painful sex occurs, treating the vaginal tissue with Osphena® can help improve comfort and prevent these symptoms from worsening.
Actor Portrayal79% of women
with VVA report symptoms of vaginal dryness, which can even make everyday movements uncomfortable.
WHY SO DRY?
Actor Portrayal59% of women
with VVA report symptoms of painful intercourse and 54% of these women consider their painful intercourse to be moderate to severe.
WHY SEX HURTS?From years of experience caring for menopausal women, Dr. Barb DePree knows firsthand that most women are often unprepared for the two most common bothersome symptoms of menopause: vaginal dryness and painful intercourse.
Dr. Barb DePree, OB/GYN, women's healthcare provider and menopause care specialist, is a paid spokesperson for Duchesnay USA.
Your key to Osphena® savings
Osphena® provides several ways to save on your prescription.
The Osphena at Home® mail order program offers the lowest available price and delivers your medication conveniently and discreetly to your doorstep.
OSPHENA® SAVINGS

